Is Obesity May Affect Kidney Function In Women With Type 2 diabetes?

A study funded by the National Key Research and Development Program and the Key R&D Projects of Jiangsu Province revealed that obesity might negatively affect kidney function in people with type 2 diabetes, particularly in women.

Is Obesity May Affect Kidney Function In Women With Type 2 diabetes?

The new study was published in the Journal of Clinical Endocrinology & Metabolism of Endocrine Society. The research, “Body Mass Index and Risk of Diabetic Nephropathy: A Mendelian Randomization Study,” was posted online before the printing.

The data for the research was from the BioBank Japan Project. Researchers analyzed body mass index data from 158,284 East Asian adults. The study concluded that genetic evidence showed that higher body mass index levels were associated with an increased risk of diabetic kidney disease and that 3,972 people with type 2 diabetes had decreased levels of renal filtration rate.

However, the researchers recorded that body mass index was not linked to the increased level of proteins in urine. It was found that women with obesity and type 2 diabetes had a greater risk of diabetic kidney disease than men. 

Zhi-Hong Liu, M.D., Jinling Hospital and Nanjing University School of Medicine in Nanjing, China, stated that Our research sheds light on how obesity contributes to the incidence and progression of diabetic nephropathy in people with type 2 diabetes, particularly for women.

He further added that managing your blood pressure and blood sugar may not be enough to slow the progression to end-stage renal disease, and our study shows how important it is for people with diabetes to also manage their weight.

High blood pressure and high blood sugar levels cause the condition of Diabetic nephropathy in patients. Diabetic nephropathy is the deterioration of kidney function in people with diabetes.

Kidney diseases are the ninth leading cause of death in the United States of America, and approximately one in every three adults with diabetes has chronic kidney disease. Over time, kidney disease progresses to end-stage kidney disease. And patients with end-stage kidney disease often need a kidney transplant to stay alive. 

Zhi-Hong Liu advised that people with diabetes and obesity should have their kidneys checked more often as they are at high risk. In addition, he assured that while chronic kidney disease has no cure, early detection and obesity treatment could slow the progression to end-stage kidney disease.

The other authors of the research were: Jingru Lu of Jinling Hospital and Nanjing University School of Medicine; Xiaoshuang Liu and Xiang Li of Ping An Healthcare Technology in Beijing, China; Ping An Health Cloud Company Limited and Ping An International Smart City Technology Co., Ltd; Song Jiang, Shuyan Kan, Yu An and Chunxia Zheng of Jinling Hospital; and Guotong Xie of Ping An Healthcare Technology in Beijing, China.

All we know about the Endocrine Society

The Endocrine Society includes scientists, physicians, educators, nurses, and students in 122 countries with more than 18,000 members. 

Endocrinologists are specialists who solve the most critical health issues of today’s world. Then that can be bone health, hormone-related cancers, or vary from diabetes and obesity to infertility.

The Endocrine Society is the oldest and largest organization in the world, which has scientists devoted to hormone research and physicians who care for people with hormone-related conditions.